Burn-Severe
Severe Burn
Description
Acute severe burn across the entire body.
Burn Distribution
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Segment Validation
Segment 1
Initiate a severe burn with 30% TBSA. Run for 1 hr.
| Property Name | Validation | Engine Value | Percent Error | Percent Change | Notes |
|---|---|---|---|---|---|
| ThermalBurn-TotalBodySurfaceArea | EqualTo 0.30 [187] | 0.300 | 0.00% | Directly set. | |
| HeartRate(1/min) | GreaterThan Moderate Segment1 (75.3) [187] | 84.4 | 12.10% | Greater tachycardia than moderate. | |
| MeanArterialPressure(mmHg) | LessThan Moderate Segment1 (95.5) [332] | 95.9 | 0.38% | Greater hypotension than moderate due to burn shock/hypovolemia. | |
| SystolicArterialPressure(mmHg) | LessThan Moderate Segment1 (114) [332] | 114 | -0.33% | Greater decrease than moderate. | |
| DiastolicArterialPressure(mmHg) | LessThan Moderate Segment1 (74.4) [332] | 76.4 | 2.65% | Greater decrease than moderate. | |
| CardiacOutput(L/min) | LessThan Moderate Segment1 (5.92) [332] | 6.27 | 6.04% | Greater reduction than moderate in early burn shock. | |
| SystemicVascularResistance(mmHg_s/mL) | GreaterThan Moderate Segment1 (0.920) [332] | 0.870 | -5.43% | Greater compensatory vasoconstriction than moderate. | |
| BloodVolume(L) | LessThan Moderate Segment1 (5.48) [332] | 5.46 | -0.46% | Greater intravascular loss than moderate due to capillary leak/third spacing. | |
| CentralVenousPressure(mmHg) | LessThan Moderate Segment1 (4.71) [332] | 4.80 | 1.96% | Further reduced preload than moderate. | |
| Aorta-Oxygen-PartialPressure(mmHg) | EqualTo Moderate Segment1 (89.2) [187] | 83.7 | -6.13% | Oxygenation may remain near baseline without inhalation injury; allow mild deviation. | |
| Aorta-CarbonDioxide-PartialPressure(mmHg) | LessThanEqualTo Moderate Segment1 (38.0) [187] | 38.1 | 0.13% | Continued hypocapnia possible with hyperventilation. | |
| OxygenSaturation | EqualTo Moderate Segment1 (0.973) [187] | 0.965 | -0.80% | SaO2 typically preserved without inhalation injury; allow mild deviation. | |
| RespirationRate(1/min) | GreaterThan Moderate Segment1 (12.4) [187] | 13.2 | 6.17% | Greater respiratory drive than moderate. | |
| TotalAlveolarVentilation(L/min) | GreaterThan Moderate Segment1 (4.73) [187] | 5.54 | 17.26% | Higher ventilation than moderate. | |
| EndTidalCarbonDioxidePressure(mmHg) | LessThan Moderate Segment1 (36.5) [187] | 36.5 | 0.02% | Lower ETCO2 than moderate with stronger hyperventilation. | |
| CoreTemperature(degC) | GreaterThan Moderate Segment1 (37.3) [186] | 37.9 | 1.54% | More pronounced hypermetabolic/stress response than moderate. | |
| SkinTemperature(degC) | LessThan Moderate Segment1 (28.2) [186] | 29.4 | 4.17% | Greater heat loss impact than moderate. | |
| TotalMetabolicRate(W) | GreaterThan Moderate Segment1 (91.7) [186] | 107 | 16.51% | Greater hypermetabolic response than moderate. | |
| UrineProductionRate(mL/min) | LessThan Moderate Segment1 (0.840) [311] | 0.608 | -27.60% | Further decreased urine output than moderate due to reduced renal perfusion. | |
| ExtracellularFluidVolume(L) | GreaterThan Moderate Segment1 (8.70) [332] | 8.47 | -2.70% | Greater third spacing/edema than moderate. | |
| ExtravascularFluidVolume(L) | GreaterThan Moderate Segment1 (34.0) [332] | 33.8 | -0.69% | Greater capillary leak-driven extravascular fluid than moderate. |
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| Property Name | Engine Value |
|---|---|
| Patient-Weight(kg) | 76.7 |
| ECG-Lead3ElectricPotential(mV) | -0.0320 |
| HeartRate(1/min) | 84.4 |
| HeartStrokeVolume(mL) | 74.3 |
| HeartEjectionFraction | 0.545 |
| BloodVolume(L) | 5.46 |
| ExtravascularFluidVolume(L) | 33.8 |
| ArterialPressure(mmHg) | 79.1 |
| MeanArterialPressure(mmHg) | 95.9 |
| SystolicArterialPressure(mmHg) | 114 |
| DiastolicArterialPressure(mmHg) | 76.4 |
| CardiacOutput(L/min) | 6.27 |
| HemoglobinContent(g) | 821 |
| CentralVenousPressure(mmHg) | 4.80 |
| PulmonaryCapillariesWedgePressure(mmHg) | 6.17 |
| TidalVolume(mL) | 571 |
| TotalLungVolume(mL) | 2.24e+03 |
| RespirationRate(1/min) | 13.2 |
| OxygenSaturation | 0.965 |
| CarbonDioxideSaturation | 0.0262 |
| EndTidalCarbonDioxideFraction | 0.0480 |
| EndTidalCarbonDioxidePressure(mmHg) | 36.5 |
| TotalAlveolarVentilation(L/min) | 5.54 |
| TranspulmonaryPressure(cmH2O) | 4.92 |
| CoreTemperature(degC) | 37.9 |
| SkinTemperature(degC) | 29.4 |
| RespiratoryExchangeRatio | 0.719 |
| OxygenConsumptionRate(mL/min) | 354 |
| CarbonDioxideProductionRate(mL/min) | 255 |
| GlomerularFiltrationRate(mL/min) | 62.4 |
| RenalBloodFlow(L/min) | 0.802 |
| UrineProductionRate(mL/min) | 0.608 |
| LeftAfferentArterioleResistance(mmHg_min/mL) | 0.0581 |
| RightAfferentArterioleResistance(mmHg_min/mL) | 0.0581 |
| SystemicVascularResistance(mmHg_s/mL) | 0.870 |
| LeftAlveoli-Pressure(cmH2O) | 1.03e+03 |
| RightAlveoli-Pressure(cmH2O) | 1.03e+03 |
| Pericardium-Volume(mL) | 15.0 |
| Pericardium-Pressure(mmHg) | 1.00 |
| Trachea-Oxygen-PartialPressure(mmHg) | 112 |
| Trachea-CarbonDioxide-PartialPressure(mmHg) | 36.5 |
| LeftLungPulmonary-Oxygen-PartialPressure(mmHg) | 111 |
| RightLungPulmonary-Oxygen-PartialPressure(mmHg) | 108 |
| LeftLungPulmonary-CarbonDioxide-PartialPressure(mmHg) | 38.1 |
| RightLungPulmonary-CarbonDioxide-PartialPressure(mmHg) | 38.9 |
| LeftAlveoli-Oxygen-PartialPressure(mmHg) | 111 |
| LeftAlveoli-CarbonDioxide-PartialPressure(mmHg) | 38.1 |
| RightAlveoli-Oxygen-PartialPressure(mmHg) | 108 |
| RightAlveoli-CarbonDioxide-PartialPressure(mmHg) | 39.0 |
| Aorta-Oxygen-PartialPressure(mmHg) | 83.7 |
| Aorta-CarbonDioxide-PartialPressure(mmHg) | 38.1 |
| VenaCava-Oxygen-PartialPressure(mmHg) | 35.7 |
| VenaCava-CarbonDioxide-PartialPressure(mmHg) | 44.9 |
| RightTubules-Sodium-Concentration(g/L) | 4.90 |
| LeftTubules-Sodium-Concentration(g/L) | 4.90 |
| Oxygen-AlveolarTransfer(mL/min) | 300 |
| CarbonDioxide-AlveolarTransfer(mL/min) | -187 |
| Epinephrine-BloodConcentration(ug/L) | 0.0361 |
| Epinephrine-SystemicMassCleared(ug) | 11.6 |
| Norepinephrine-BloodConcentration(ug/L) | 0.224 |
| Norepinephrine-SystemicMassCleared(ug) | 40.0 |
Scenario Output Plots
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