CDM Tables

The following tables describe a patient for Pulse to simulate


Patient

Data used to configure the patient.

Property Name Type Definition
Age SEScalarTime Patient age.
BasalMetabolicRate SEScalarPower The life-sustaining metabolic rate.
BodyFatFraction SEScalar0To1 Total mass of fat divided by total body mass; body fat includes essential body fat and storage body fat.
DiastolicArterialPressureBaseline SEScalarPressure The starting minimum pressure in the aorta over the course of a cardiac cycle.
BodyDensity SEScalarMassPerVolume The mass of the body divided by the volume of the body.
ExpiratoryReserveVolume SEScalarVolume The maximum amount of air that can be exhaled from the end-expiratory position.
HeartRateBaseline SEScalarFrequency The resting heart rate.
RightLungRatio SEScalar0To1 The ratio of total lung surface area that is associated with the right lung.
Name String Patient Identifier.
Height SEScalarLength Patient height.
RespirationRateBaseline SEScalarFrequency The resting respiration rate.
ResidualVolume SEScalarVolume The volume of air remaining in the lungs after a maximal exhalation.
FunctionalResidualCapacity SEScalarVolume The volume of air remaining in the lungs after a passive expiration.
InspiratoryReserveVolume SEScalarVolume The maximal volume that can be inhaled from the end-inspiratory level.
TidalVolumeBaseline SEScalarVolume The starting volume of air moved into or out of the lungs during normal respiration.
VitalCapacity SEScalarVolume The maximum amount of air a person can expel from their lungs after a maximum inhalation.
Sex Enum ePatient_SexTable
SkinSurfaceArea SEScalarArea The surface area of the skin surface of the body.
HeartRateMaximum SEScalarFrequency The maximum heart rate the patient can withstand.
Weight SEScalarMass Patient weight.
AlveoliSurfaceArea SEScalarArea The surface area of the alveoli for gas diffusion.
MeanArterialPressureBaseline SEScalarPressure The resting mean arterial pressure.
InspiratoryCapacity SEScalarVolume The sum of IRV and TV.
BloodVolumeBaseline SEScalarVolume The total volume of fluid within the cardiovascular system.
LeanBodyMass SEScalarMass Component of body composition after subtracting body fat weight.
SystolicArterialPressureBaseline SEScalarPressure The starting maximum pressure in the aorta over the course of a cardiac cycle.
HeartRateMinimum SEScalarFrequency The minimum heart rate the patient can withstand.
TotalLungCapacity SEScalarVolume The volume of air in the lungs at maximal inflation.

ePatient_Sex

Enumeration for patient sex.

Property Name Type Definition
Male Enum Male patient.
Female Enum Female patient.

The following tables describe the physiological states of a patient Pulse supports.


ePatient_Event

Enumeration for states the patient can enter and exit out of.

Property Name Type Definition
Antidiuresis Enum Low urine flow.
Asystole Enum Represents no cardiac electrical activity.
Bradycardia Enum The heart rate is slowed to below 60 beats per minute.
Bradypnea Enum The state at which the respiratory rate has fallen 10 breaths per minute.
BrainOxygenDeficit Enum A lack of oxygen in the brain. Death will occur ~30min.
CardiacArrest Enum Sudden, unexpected loss of heart function, breathing, and consciousness.
CardiogenicShock Enum Inadequate blood circulation due to failure of the heart ventricles (Cardiac Index < 2.2 L/min m2).
CriticalBrainOxygenDeficit Enum A critical lack of oxygen in the brain. Death in under 10min.
Dehydration Enum A loss of more fluid than is taken in (More than 3% loss of resting fluid mass).
Diuresis Enum High urine flow.
Fasciculation Enum Brief spontaneous contractions of muscle fibers.
Fatigue Enum The body is using energy above the Basal Metabolic Rate.
FunctionalIncontinence Enum Uncontrolled bladder release due to a full bladder.
Hypercapnia Enum State at which the arterial carbon dioxide partial pressure has exceeded 60 mmHg.
Hyperglycemia Enum An excess of glucose in the bloodstream (> 200 mg/dL).
Hyperthermia Enum The condition of having a body temperature greatly above normal (> 38 C).
Hypoglycemia Enum Low glucose in the bloodstream (< 70 mg/dL).
Hypothermia Enum The condition of having a body temperature greatly below normal (< 35 C).
Hypoxia Enum State at which the arterial oxygen partial pressure has fallen below 65 mmHg.
HypovolemicShock Enum The blood volume has dropped below 65% of its normal value.
IntracranialHypertension Enum Intracranial pressure is greater than 25 mmHg.
IntracranialHypotension Enum Intracranial pressure is lower than 7 mmHg.
IrreversibleState Enum An unrecoverable patient state. The engine will cease calculating when this event occurs.
Ketoacidosis Enum A form of metabolic acidosis where the anion gap is driven by the rise in ketones.
LacticAcidosis Enum A form of metabolic acidosis where the blood lactate concentration rises.
MaximumPulmonaryVentilationRate Enum The maximum pulmonary ventilation rate has been reached.
MetabolicAcidosis Enum A condition where the body is producing excess acids. (pH < 7.35).
MetabolicAlkalosis Enum A condition where the body is producing excess bases. (pH > 7.45).
MildAcuteRespiratoryDistress Enum Mild impairment of the alveoli, reducing gas exchange within the lungs. (CarricoIndex [201,300] mmHg)
ModerateAcuteRespiratoryDistress Enum Moderate impairment of the alveoli, reducing gas exchange within the lungs. (CarricoIndex [101,200] mmHg)
MyocardiumOxygenDeficit Enum The myocardium oxygen level has decreased below 5 mmHg.
Natriuresis Enum Sodium excretion above normal levels.
NutritionDepleted Enum The stomach is empty.
PulselessRhythm Enum The state at which the heart has stopped beating.
RenalHypoperfusion Enum Low blood flow to the kidneys.
RespiratoryAcidosis Enum An increase of CO2 concentration in the bloodstream and a decrease in blood pH.
RespiratoryAlkalosis Enum An decrease of CO2 concentration in the bloodstream and a increase in blood pH.
StartOfCardiacCycle Enum The Patient is starting a new heart beat.
StartOfExhale Enum Patient is starting to exhale.
StartOfInhale Enum Patient is starting to inhale.
SevereAcuteRespiratoryDistress Enum Severe impairment of the alveoli, reducing gas exchange within the lungs. (CarricoIndex [0,100] mmHg)
Tachycardia Enum The heart rate is elevated above 100 beats per minute.
Tachypnea Enum A breathing rate above 20 breaths per minute.

The following tables describe the conditions that can be applied to the patient before starting the simulation


ChronicAnemia

Condition characterized by reduced red blood cells, which leads to reduced oxygen carrying capacity. Implemented by reducing the amount of hemoglobin in the blood.

Property Name Type Definition
ReductionFactor SEScalar0To1 The fraction to reduce the amount of hemoglobin by.

ChronicObstructivePulmonaryDisease

Chronic Obstructive Pulmonary Disease (COPD) is an obstructive lung disease characterized by chronically reduced airflow into the lungs. Unlike asthma, the reduction in airflow does not generally improve with medication. When tissue damage occurs primarily in the airways, the condition is called chronic bronchitis. When tissue destruction is focused in the alveoli, the condition is called emphysema. COPD is a manifestation of both conditions, although one condition may dominate.

Property Name Type Definition
EmphysemaSeverity SEScalar0To1 Scale of affect, 0 being none, 1 being the highest possible.
BronchitisSeverity SEScalar0To1 Scale of affect, 0 being none, 1 being the highest possible.

ChronicPericardialEffusion

Pericardial effusion ("fluid around the heart") is an abnormal accumulation of fluid in the pericardial cavity. Because of the limited amount of space in the pericardial cavity, fluid accumulation leads to an increased intrapericardial pressure which can negatively affect heart function. A pericardial effusion with enough pressure to adversely affect heart function is called cardiac tamponade. Pericardial effusion usually results from a disturbed equilibrium between the production andre-absorption of pericardial fluid, or from a structural abnormality that allows fluid to enter the pericardial cavity. Normal levels of pericardial fluid are from 15 to 50 mL.

Property Name Type Definition
AccumulatedVolume SEScalarVolume The amount of fluid in the pericardial cavity.

ChronicRenalStenosis

Narrowing of the renal artery.

Property Name Type Definition
LeftKidneySeverity SEScalar0To1 Scale of affect, 0 being none, 1 being the highest possible.
RightKidneySeverity SEScalar0To1 Scale of affect, 0 being none, 1 being the highest possible.

ChronicVentricularSystolicDysfunction

Impairment of the ventricular contraction, reducing the ability of the heart to pump blood.


ConsumeMeal

Consume nutrients into the body along with a time elapsed since this meal.

Property Name Type Definition
Meal SEMeal MealTable
MealFile String File containing a meal objet with properties to initialize the system with.

ImpairedAlveolarExchange

Generic way to specify the effectivness of alveolar exchange.

Property Name Type Definition
ImpairedSurfaceArea SEScalarArea Surface Area of the impaired alveoli.
ImpairedFraction SEScalar0To1 Surface Area Fraction of the impaired alveoli.

LobarPneumonia

Lobar pneumonia is a form of pneumonia that affects one or more lobes of the lungs. As fluid fills portions of the lung it becomes more difficult to breath and the gas diffusion surface area in the alveoli is reduced.

Property Name Type Definition
LeftLungAffected SEScalar0To1 Fraction of the Left Lung Affected.
Severity SEScalar0To1 Scale of affect, 0 being none, 1 being the highest possible.
RightLungAffected SEScalar0To1 Fraction of the Left Lung Affected.

The following tables describe the system data that is calculated each time step


BloodChemistrySystem
Property Name Type Definition
RedBloodCellCount SEScalarAmountPerVolume Total number of red blood cells in the blood.
BloodPH SEScalar Measure of acidity or basicity of the blood.
VenousOxygenPressure SEScalarPressure Partial pressure of oxygen in the vena cava.
ShuntFraction SEScalar0To1 Fraction of the blood flow that bypasses the alveoli; therefore, does not engage is gas exchange.
VolumeFractionNeutralPhospholipidInPlasma SEScalar0To1 Fraction of the plasma that is made up of neutral phospholipids.
BloodUreaNitrogenConcentration SEScalarMassPerVolume The BUN concentration in the blood.
PulseOximetry SEScalar0To1 The fraction of hemoglobin with bound oxygen as measured optically, which can include Carbon Monoxide.
CarbonMonoxideSaturation SEScalar0To1 The fraction of hemoglobin that is carbon monoxide bound.
PulmonaryArterialCarbonDioxidePressure SEScalarPressure Partial pressure of carbon dioxide in the pulmonary arteries.
StrongIonDifference SEScalarAmountPerVolume Difference between the positive and negative strong ion concentrations in the blood.
TotalProteinConcentration SEScalarMassPerVolume The concentration of urea in the blood.
VolumeFractionNeutralLipidInPlasma SEScalar0To1 Fraction of the plasma that is made up of neutral lipids.
VenousCarbonDioxidePressure SEScalarPressure Partial pressure of carbon dioxide in the vena cava.
PulmonaryVenousOxygenPressure SEScalarPressure Partial pressure of oxygen in the pulmonary veins.
ArterialCarbonDioxidePressure SEScalarPressure Partial pressure of carbon dioxide in the aorta.
BloodDensity SEScalarMassPerVolume Mass per unit volume of the blood.
HemoglobinContent SEScalarMass The total amount of hemoglobin in the blood.
PulmonaryVenousCarbonDioxidePressure SEScalarPressure Partial pressure of carbon dioxide in the pulmonary veins.
CarbonDioxideSaturation SEScalar0To1 The fraction of hemoglobin that is carbon dioxide bound.
Phosphate SEScalarAmountPerVolume Sum of all inorganic phosphate in the blood.
WhiteBloodCellCount SEScalarAmountPerVolume Total number of white blood cells in the blood.
Hematocrit SEScalar0To1 Volume percentage of red blood cells in the blood.
OxygenSaturation SEScalar0To1 The fraction of hemoglobin that is oxygen bound.
PulmonaryArterialOxygenPressure SEScalarPressure Partial pressure of oxygen in the pulmonary arteries.
PlasmaVolume SEScalarVolume Volume of the plasma.
ArterialOxygenPressure SEScalarPressure Partial pressure of oxygen in the aorta.
BloodSpecificHeat SEScalarHeatCapacitancePerMass The amount of energy required to raise one kilogram of blood by one degree Celsius.

CardiovascularSystem
Property Name Type Definition
ArterialPressure SEScalarPressure The current arteial pressure.
PulmonaryMeanShuntFlow SEScalarVolumePerTime The average blood flow diverted from the pulmonary capillaries (not oxygenated) over the course of a cardiac cycle.
MeanArterialPressure SEScalarPressure The average arterial pressure throughout each cardiac cycle.
PulmonarySystolicArterialPressure SEScalarPressure The maximum pressure in the pulmonary arteries over the course of a cardiac cycle.
PulmonaryVascularResistance SEScalarFlowResistance The resistance offered by the pulmonary circulation.
HeartEjectionFraction SEScalar0To1 The current pressure in the aorta.
CardiacOutput SEScalarVolumePerTime The volume of blood being pumped from the heart in a given time interval.
It is defined as the heart rate multiplied by the stroke volume.
PulmonaryMeanCapillaryFlow SEScalarVolumePerTime The average blood flow in the pulmonary capillaries over the course of a cardiac cycle.
IntracranialPressure SEScalarPressure The pressure inside the skull. Equal to the cerebral blood pressure with the cerebrospinal fluid pressure being assumed equal.
PulmonaryCapillariesWedgePressure SEScalarPressure The pressure within the pulmonary capillaries.
PulmonaryDiastolicArterialPressure SEScalarPressure The minimum pressure that occurs in the pulmonary arteries over the course of a cardiac cycle.
HeartRhythm Enum Current heart rhythm.
MeanArterialCarbonDioxidePartialPressureDelta SEScalarPressure The change of the the mean of the partial pressure of carbon dioxide in the aorta from the previous cardiac cycle.
CerebralPerfusionPressure SEScalarPressure The difference between the mean arterial pressure and the cerebral blood pressure. Defines the hydrostatic diffusion gradient.
CardiacIndex SEScalarVolumePerTimeArea Relates heart performance to the size of the individual.
PulmonaryMeanArterialPressure SEScalarPressure The average pressure that occurs in the pulmonary arteries over the course of a cardiac cycle.
HeartStrokeVolume SEScalarVolume The volume of blood pumped from the left ventricle in one contraction.
MeanArterialCarbonDioxidePartialPressure SEScalarPressure The mean of the partial pressure of carbon dioxide in the aorta over a cardiac cycle.
MeanCentralVenousPressure SEScalarPressure The average pressure in the vena cava over the course of a cardiac cycle.
SystemicVascularResistance SEScalarFlowResistance The resistance to blood flow through the entire systemic vasculature, not including the pulmonary circulation.
PulmonaryArterialPressure SEScalarPressure The current pressure in the pulmonary arteries.
PulmonaryVascularResistanceIndex SEScalarPressureTimePerVolumeArea Relates pulmonary circulation performance to the size of the individual.
CerebralBloodFlow SEScalarVolumePerTime The rate of blood flow into the skull, thus supplying the brain.
MeanSkinFlow SEScalarVolumePerTime The blood flow to the skin averaged over the current cardiac cycle time.
DiastolicArterialPressure SEScalarPressure The minimum pressure in the aorta over the course of a cardiac cycle.
PulsePressure SEScalarPressure The difference between the systolic and diastolic pressures.
BloodVolume SEScalarVolume The total volume of fluid within the cardiovascular system.
SystolicArterialPressure SEScalarPressure The maximum pressure in the aorta over the course of a cardiac cycle.
HeartRate SEScalarFrequency The fraction of the blood that is pumped out of the ventricle during a cardiac cycle.
CentralVenousPressure SEScalarPressure The instantaneous pressure of the venus return.

DrugSystem
Property Name Type Definition
SedationLevel SEScalar0To1
BronchodilationLevel SEScalarNegative1To1
NeuromuscularBlockLevel SEScalar0To1
PulsePressureChange SEScalarPressure
TubularPermeabilityChange SEScalarNegative1To1
MeanBloodPressureChange SEScalarPressure
HeartRateChange SEScalarFrequency
TidalVolumeChange SEScalarVolume
PupillaryResponse SEPupillaryResponse PupillaryResponseTable
RespirationRateChange SEScalarFrequency

EndocrineSystem
Property Name Type Definition
InsulinSynthesisRate SEScalarAmountPerTime Insulin production rate.

EnergySystem
Property Name Type Definition
CreatinineProductionRate SEScalarAmountPerTime The generation of creatinine in the muscle tissue per.
TotalMetabolicRate SEScalarPower The basal metabolic rate plus additional energy expenditure rates due to activity.
LactateProductionRate SEScalarAmountPerTime The molar amount of lactate generated on the tissue level from anaerobic metabolism.
SweatRate SEScalarMassPerTime Mass of sweat generated per unit time due to elevated core temperature.
ExerciseMeanArterialPressureDelta SEScalarPressure The pressure delta that occurs during exercise. Used to modify the baroreceptor set-point.
FatigueLevel SEScalar0To1 The exhaustion level of the body, or inability to perform physical exercise.
KetoneProductionRate SEScalarAmountPerTime The molar amount of ketones generated in the liver.
AchievedExerciseLevel SEScalar0To1 The fraction of how much of the requested exercise the patient is able to achieve. 1.0 means the the patient is performing at the requested level. Nan is the patient is not exercising (no Action)
SkinTemperature SEScalarTemperature The skin surface temperature.
TotalWorkRateLevel SEScalar0To1 The current patient work rate above basal over the maximum work rate capable by the patient.
CoreTemperature SEScalarTemperature The internal body temperature.

GastrointestinalSystem
Property Name Type Definition
StomachContents SENutrition NutritionTable
ChymeAbsorptionRate SEScalarVolumePerTime Rate of the absorption of nutrients from chyme into the blood stream.

HepaticSystem

NervousSystem
Property Name Type Definition
BaroreceptorHeartElastanceScale SEScalar Heart elastance multiplier used to scale the heart rate due to baroreceptor feedback.
ChemoreceptorHeartRateScale SEScalar Heart rate multiplier used to scale the heart rate due to baroreceptor feedback.
BaroreceptorHeartRateScale SEScalar Heart rate multiplier used to scale the heart rate due to baroreceptor feedback.
BaroreceptorResistanceScale SEScalar Cardiovascular resistance multiplier used to scale the heart rate due to baroreceptor feedback.
ChemoreceptorHeartElastanceScale SEScalar Heart elastance multiplier used to scale the heart rate due to baroreceptor feedback.
LeftEyePupillaryResponse SEPupillaryResponse PupillaryResponseTable
RightEyePupillaryResponse SEPupillaryResponse PupillaryResponseTable
BaroreceptorComplianceScale SEScalar Cardiovascular compliance multiplier used to scale the heart rate due to baroreceptor feedback.

PhysiologySystem

PupillaryResponse
Property Name Type Definition
ReactivityModifier SEScalarNegative1To1 Change in pupil recation time -1 complete reduction/no response, 0 is normal, and 1 is the fastest reaction time.
SizeModifier SEScalarNegative1To1 Pupil size change from normal. -1 is fully constricted, 0 is no change, +1 is fully dilated.
ShapeModifier SEScalarNegative1To1 Percentage change in pupil shape from normal. Positive is vertical ovoid. Negative is horizontal ovoid.

RenalSystem
Property Name Type Definition
LeftReabsorptionFiltrationCoefficient SEScalarVolumePerTimePressure Value which determines how much of a substance is reabsorbed into the blood stream in the left Kidney.
LeftPeritubularCapillariesHydrostaticPressure SEScalarPressure Pressure generated by the fluid in the peritubular capillaries in the left Kidney.
RenalBloodFlow SEScalarVolumePerTime Blood flow into the kidney that is not filtered into the tubules.
RightGlomerularFluidPermeability SEScalarVolumePerTimePressureArea Permeability coeffitient of the capillary tissue in the left Kidney.
LeftGlomerularFiltrationCoefficient SEScalarVolumePerTimePressure Calculated for each substance to determine ease of transport into the tubules in the left Kidney.
LeftGlomerularFiltrationRate SEScalarVolumePerTime Flow rate of filtrate into the tubules in left Kidney.
LeftGlomerularFluidPermeability SEScalarVolumePerTimePressureArea Permeability coeffitient of the capillary tissue in the left Kidney.
LeftTubularHydrostaticPressure SEScalarPressure Preassure generated by the fluid in the tubules in the left Kidney.
LeftFiltrationFraction SEScalar0To1 Scalar used to compute reabsorption for substances in left Kidney.
RenalPlasmaFlow SEScalarVolumePerTime Plasma flow into the kidney that is not filtered into the tubules.
LeftAfferentArterioleResistance SEScalarFlowResistance resistance to flow going into the glomerular capillaries in the left Kidney
LeftReabsorptionRate SEScalarVolumePerTime Rate at which fluid or a substance is transported into the peritubular capillaries in the left Kidney.
RightFiltrationFraction SEScalar0To1 Scalar used to compute reabsorption for substances in left Kidney.
RightPeritubularCapillariesHydrostaticPressure SEScalarPressure Pressure generated by the fluid in the peritubular capillaries in the left Kidney.
RightAfferentArterioleResistance SEScalarFlowResistance resistance to flow going into the glomerular capillaries in the right Kidney
UrineOsmolality SEScalarOsmolality The osmolar pressure contributions of the sodium, urea and glucose divided by the mass of the fluid.
GlomerularFiltrationRate SEScalarVolumePerTime Flow rate of filtrate into the tubules.
LeftNetReabsorptionPressure SEScalarPressure Total pressure directed into the peritubular capillaries in the left Kidney.
RenalVascularResistance SEScalarFlowResistance Total resistance o f the kidney vasculature.
RightTubularReabsorptionFiltrationSurfaceArea SEScalarArea Surface ares of the tubules which is subject to fluid transport (reabsorption) in the left Kidney.
LeftTubularOsmoticPressure SEScalarPressure Pressure generated by substances in the tubules in the left Kidney.
LeftBowmansCapsulesHydrostaticPressure SEScalarPressure Pressure generated from fluid in the bowmans capsules in the left Kidney.
RightBowmansCapsulesOsmoticPressure SEScalarPressure Pressure generated from substances in the bowmans capsules in the right Kidney.
RightTubularHydrostaticPressure SEScalarPressure Preassure generated by the fluid in the tubules in the left Kidney.
UrineOsmolarity SEScalarOsmolarity The osmolar pressure contributions of the sodium, urea and glucose divided by the volume of the fluid.
LeftGlomerularCapillariesHydrostaticPressure SEScalarPressure Pressure generated from fluid in the glomerular capillaries in the left Kidney.
RightNetReabsorptionPressure SEScalarPressure Total pressure directed into the peritubular capillaries in the left Kidney.
RightGlomerularFiltrationSurfaceArea SEScalarArea Surface area of glomerular capillaries that experiance filtration in the left Kidney.
LeftTubularReabsorptionFluidPermeability SEScalarVolumePerTimePressureArea Permeability of the tissue in the tubules, influencing resistance to flow into peritubular capillaries in the left Kidney.
LeftBowmansCapsulesOsmoticPressure SEScalarPressure Pressure generated from substances in the bowmans capsules in the left Kidney.
RightNetFiltrationPressure SEScalarPressure Total pressure directed into the tubules in the left Kidney.
FiltrationFraction SEScalar0To1 Scalar used to compute reabsorption for substances.
RightGlomerularFiltrationCoefficient SEScalarVolumePerTimePressure Calculated for each substance to determine ease of transport into the tubules in the left Kidney.
RightTubularOsmoticPressure SEScalarPressure Pressure generated by substances in the tubules in the left Kidney.
RightPeritubularCapillariesOsmoticPressure SEScalarPressure Pressure generated by the substance concentration in the peritubular capillaries in the left Kidney.
LeftPeritubularCapillariesOsmoticPressure SEScalarPressure Pressure generated by the substance concentration in the peritubular capillaries in the left Kidney.
LeftTubularReabsorptionFiltrationSurfaceArea SEScalarArea Surface ares of the tubules which is subject to fluid transport (reabsorption) in the left Kidney.
UrinationRate SEScalarVolumePerTime Rate that fluid exits the bladder.
UrineUreaNitrogenConcentration SEScalarMassPerVolume Scaled concentration of Urea in the bladder.
RightGlomerularCapillariesOsmoticPressure SEScalarPressure Pressure generated from substances in the capillaries in the left Kidney.
RightGlomerularFiltrationRate SEScalarVolumePerTime Flow rate of filtrate into the tubules in left Kidney.
RightTubularReabsorptionFluidPermeability SEScalarVolumePerTimePressureArea Permeability of the tissue in the tubules, influencing resistance to flow into peritubular capillaries in the left Kidney.
UrineVolume SEScalarVolume The volume of the urine in the bladder.
LeftNetFiltrationPressure SEScalarPressure Total pressure directed into the tubules in the left Kidney.
RightReabsorptionRate SEScalarVolumePerTime Rate at which fluid or a substance is transported into the peritubular capillaries in the left Kidney.
UrineProductionRate SEScalarVolumePerTime The rate of fluid flow to the bladder.
LeftGlomerularFiltrationSurfaceArea SEScalarArea Surface area of glomerular capillaries that experiance filtration in the left Kidney.
RightReabsorptionFiltrationCoefficient SEScalarVolumePerTimePressure Value which determines how much of a substance is reabsorbed into the blood stream in the left Kidney.
LeftGlomerularCapillariesOsmoticPressure SEScalarPressure Pressure generated from substances in the capillaries in the left Kidney.
RightBowmansCapsulesHydrostaticPressure SEScalarPressure Pressure generated from fluid in the bowmans capsules in the right Kidney.
UrineSpecificGravity SEScalar The density of the fluid relative to water.
RightGlomerularCapillariesHydrostaticPressure SEScalarPressure Pressure generated from fluid in the glomerular capillaries in the left Kidney.
LeftEfferentArterioleResistance SEScalarFlowResistance Resistance to flow into the peritubular capillaries in the left Kidney.
RightEfferentArterioleResistance SEScalarFlowResistance Resistance to flow into the peritubular capillaries in the left Kidney.

RespiratorySystem
Property Name Type Definition
TotalDeadSpaceVentilation SEScalarVolumePerTime The air flow to the dead space.
ExpiratoryFlow SEScalarVolumePerTime Instantaneous airflow out of the lungs (negative value when inhaling)
EndTidalCarbonDioxideFraction SEScalar0To1 The fraction of CarbonDioxide in the trachea that is carbon dioxide at the end of each respiratory cycle.
TidalVolume SEScalarVolume The volume of air moved into or out of the lungs during normal respiration.
EndTidalCarbonDioxidePressure SEScalarPressure The pressure of CarbonDioxide in the trachea that is carbon dioxide at the end of each respiratory cycle.
TotalPulmonaryVentilation SEScalarVolumePerTime The flow rate representing the exchange of air between the lungs and ambient air.
PulmonaryCompliance SEScalarFlowCompliance The total compliance of the lungs.
InspiratoryFlow SEScalarVolumePerTime TInstantaneous airflow into the lungs (negative value when exhaling).
TotalAlveolarVentilation SEScalarVolumePerTime The air flow to the alveoli.
PulmonaryResistance SEScalarFlowResistance The total resistance to airflow through the lungs.
SpecificVentilation SEScalar The ratio of the volume of gas entering a region of the lung following an inspiration and the end-expiratory volume of that same lung region.
RespirationDriverPressure SEScalarPressure Pressure that drives the respiratory system in generating physiologic pressures.
InspiratoryExpiratoryRatio SEScalar The ratio of the length of time of inspiration to the length of time of expiration.
TotalLungVolume SEScalarVolume The total volume of air within the lungs at any given time.
AlveolarArterialGradient SEScalarPressure Measure of the difference between the alveolar concentration of oxygen and the arterial concentration of oxygen to assess the integrity of the alveolar capillary unit..
RespirationRate SEScalarFrequency The frequency of the respiratory cycle.
TranspulmonaryPressure SEScalarPressure The pressure difference between the alveoli and the intrapleural space.
CarricoIndex SEScalarPressure The ratio of arterial partial pressure O2 and the inspired O2. O2 level in blood vs. Concentration of O2 in a breath.
RespirationMusclePressure SEScalarPressure Combined driver pressure of the muscles that contribute to inhalation and exhalation, by aiding in the expansion and contraction of the thoracic cavity.

TissueSystem

Provides data pertaining to the extracellular and intracelluar space.

Property Name Type Definition
IntracellularFluidPH SEScalar The acidity or alkalinity of the extravascular intercellular fluid.
RespiratoryExchangeRatio SEScalar The true ratio of carbon dioxide produced to oxygen consumed.
ExtracellularFluidVolume SEScalarVolume Volume of fluid outside of cells AND outside of the blood vessels.
IntracellularFluidVolume SEScalarVolume Volume of fluid in the cells outside of the blood vessels.
ExtravascularFluidVolume SEScalarVolume Total fluid volume outside of the blood vessels.
OxygenConsumptionRate SEScalarVolumePerTime The oxygen consumed on the tissue level from aerobic metabolism.
CarbonDioxideProductionRate SEScalarVolumePerTime The carbon dioxide generated on the tissue level from aerobic metabolism.

The following tables describe the are actions that may be performed on the patient


AcuteStress

Fight or flight. The body prepares to defend itself.

Property Name Type Definition
Severity SEScalar0To1 Scale of affect, 0 being none, 1 being the highest possible.

AirwayObstruction

A blockage of the Airway leading to no respiration/air flow in or out of the body.

Property Name Type Definition
Severity SEScalar0To1 Scale of affect, 0 being none, 1 being the highest possible.

Apnea

Reduction of achieved tidal volume by inhibiting the respiratory breathing mechanism (i.e., muscles of respiration). Maximum severity will stop breathing completely.

Property Name Type Definition
Severity SEScalar0To1 Scale of affect, 0 being none, 1 being the highest possible.

AsthmaAttack
Property Name Type Definition
Severity SEScalar0To1 Scale of affect, 0 being none, 1 being the highest possible.

BrainInjury

A non-localized traumatic brain injury.

Property Name Type Definition
Severity SEScalar0To1 Scale of affect, 0 being none, 1 being the highest possible.
Type Enum eBrainInjury_TypeTable

Bronchoconstriction

Constriction of the airways in the lungs due to tightening of surrounding smooth muscle.

Property Name Type Definition
Severity SEScalar0To1 Scale of affect, 0 being none, 1 being the highest possible.

CardiacArrest

Applies a non-specific cardiac arrest.

Property Name Type Definition
State Enum eSwitchTable

ChestCompressionForce

Technique used when performing cardiopulmonary resuscitation. Application of external force to the chest cavity in order to pump blood through the heart.

Property Name Type Definition
Force SEScalarForce Amount of force applied to the chest.

ChestCompressionForceScale

Technique used when performing cardiopulmonary resuscitation. Application of external force to the chest cavity in order to pump blood through the heart.

Property Name Type Definition
ForceScale SEScalar0To1 A fractional representation of the maximum force that can be applied to the chest: 0.0 is no force applied, 1.0 is maximum force applied.
ForcePeriod SEScalarTime The specified length of time the force is applied.

ChestOcclusiveDressing

Applies an occlusive dressing to either the left or right side of the chest. An occlusive dressing is an air and water-tight trauma dressing that provides immediate control of pressure and bleeding that occurs with an open pneumothorax.

Property Name Type Definition
Side Enum eSideTable
State Enum eSwitchTable

ConsciousRespiration

An ordered list of concious breath commands for the patient to preform.

Property Name Type Definition
Commands List of CommandsBreathHoldTable
ForcedExhaleTable
ForcedInhaleTable
UseInhalerTable

ConsumeNutrients

Consume nutrients into the body.

Property Name Type Definition
NutritionFile String External file containing a NutritionData definition.
Nutrition SENutrition NutritionTable

Exercise

Increase the patient's metabolic rate leading to an increase in core temperature, cardiac output, respiration rate and tidal volume.

Property Name Type Definition
Intensity SEScalar0To1 Fractional representation of the maximum patient exertion.

Hemorrhage

A hemorrhage is the loss of blood escaping from the circulatory system. Typically, a healthy person can endure a loss of 10 to 15 percent of the total blood volume without serious medical difficulties.

Property Name Type Definition
Rate SEScalarVolumePerTime The flow rate of blood exiting the specified compartment. Set to zero to stop the bleeding rate.
Compartment String Compartment where the bleeding is occurring.
Type Enum eHemorrhage_TypeTable

Intubation

Insertion of tube into the patient's airway.

Property Name Type Definition
Type Enum eIntubation_TypeTable

MechanicalVentilation

Mechanically breathing for the patient, such as with a squeeze bag or other equipment.

Property Name Type Definition
Aerosol List of SESubstanceConcentrationSubstanceConcentrationTable
Flow SEScalarVolumePerTime Flow produced.
GasFraction List of SESubstanceFractionSubstanceFractionTable
Pressure SEScalarPressure Pressure produced.

NeedleDecompression

A 14-16G intravenous caninula is inserted into the second rib-space in the mid-clavcular line. The needle is advanced until air can be aspirated into a connecting syringe. The needle is withdrawn and the caninula is left to allow air flow out of the pleural space. This effectively converts the closed pneumothorax into an open pneumothorax.

Property Name Type Definition
Side Enum eSideTable

PatientAssessmentRequest
Property Name Type Definition
Type Enum ePatientAssessment_TypeTable

PericardialEffusion

Pericardial effusion ("fluid around the heart") is an abnormal accumulation of fluid in the pericardial cavity. Because of the limited amount of space in the pericardial cavity, fluid accumulation leads to an increased intrapericardial pressure which can negatively affect heart function. A pericardial effusion with enough pressure to adversely affect heart function is called cardiac tamponade. Pericardial effusion usually results from a disturbed equilibrium between the production andre-absorption of pericardial fluid, or from a structural abnormality that allows fluid to enter the pericardial cavity. Normal levels of pericardial fluid are from 15 to 50 mL.

Property Name Type Definition
EffusionRate SEScalarVolumePerTime Rate at which fluid is filling the pericardial cavity.

SubstanceBolus

An administration of a substance that is given all at one time to raise its concentration in blood to an effective level.

Property Name Type Definition
Substance SESubstance SubstanceTable
Dose SEScalarVolume Volume of dose to administer.
AdministrationRoute Enum eSubstanceAdministration_RouteTable
Concentration SEScalarMassPerVolume Concentration of the dose to administer.

SubstanceCompoundInfusion

Continuous injection of a compound.

Property Name Type Definition
BagVolume SEScalarVolume SubstanceCompoundTable
Rate SEScalarVolumePerTime Flow rate of the infusion into the body.
SubstanceCompound SESubstanceCompound SubstanceCompoundTable

SubstanceInfusion

Continuous injection of a specific substance.

Property Name Type Definition
Rate SEScalarVolumePerTime Flow rate of the infusion into the body.
Substance SESubstance SubstanceTable
Concentration SEScalarMassPerVolume Concentration of the dose to administer.

TensionPneumothorax

A pneumothorax is an abnormal collection of air or gas in the pleural space that separates the lung from the chest wall. Like pleural effusion (liquid buildup in that space), pneumothorax may interfere with normal breathing.

Property Name Type Definition
Severity SEScalar0To1 Scale of affect, 0 being none, 1 being the highest possible.
Side Enum eSideTable
Type Enum eGateTable

Urinate

Empty the bladder of its contents.


ForcedInhale

Force air out of the lungs.

Property Name Type Definition
InspiratoryCapacityFraction SEScalar0To1 The fraction of the Inspiratory capacity that will be filled by the breath.
Period SEScalarTime Duration of the inhale.

BreathHold

Hold the patients breath. There will be no inflow or out flow of air during the specified period.

Property Name Type Definition
Period SEScalarTime Duration of the breath hold.

ForcedExhale

Force air into the lungs.

Property Name Type Definition
ExpiratoryReserveVolumeFraction SEScalar0To1 The fraction of the Expiratory Reserve Volume that is forced out of the body.
Period SEScalarTime Duration of the exhale.

UseInhaler

Administer a substance through an Inhaler. This command will represent a single press of an Inhaler.


eBrainInjury_Type

Types of Brain Injury that provided different nervous responses.

Property Name Type Definition
Diffuse Enum A brain injury dilating both eye pupils.
LeftFocal Enum A brain injury dilating the left eye pupil.
RightFocal Enum A brain injury dilating the right eye pupil.

eHemorrhage_Type

Types of Hemorrhages.

Property Name Type Definition
External Enum A loss of blood from the vascular system out of the body.
Internal Enum A loss of blood from the vascular system into a body cavity or space.

eIntubation_Type

Enumeration Types of Intubation.

Property Name Type Definition
Off Enum Remove intubation.
Esophageal Enum Insert into the Esophagus.
LeftMainstem Enum Insert into the left main stem inflating only the left lung.
RightMainstem Enum Insert into the right main stem inflating only the right lung.
Tracheal Enum Insert into the Trachea.

eSubstanceAdministration_Route

Types of Substance Administration means.

Property Name Type Definition
Intravenous Enum Injection into a vein.
Epidural Enum Injection into a epidural space.
Intraosseous Enum Injection into the bone marrow.
Intraarterial Enum Injection into an artery.
Intracardiac Enum Injection into the heart.
Intracerebral Enum Injection into the brain.
Intracerebroventricular Enum Injection into the cerebral ventricles.
Intradermal Enum Injection into the skin.
Intramuscular Enum Injection into the muscle.
Subcutaneous Enum Injection under the skin.

Nutrition

Nutritional information for eating.

Property Name Type Definition
Calcium SEScalarMass
FatDigestionRate SEScalarMassPerTime
Sodium SEScalarMass
Protein SEScalarMass
CarbohydrateDigestionRate SEScalarMassPerTime
Water SEScalarVolume
Fat SEScalarMass
ProteinDigestionRate SEScalarMassPerTime
Carbohydrate SEScalarMass

Meal

Specify an amount of time to digest the specified nutrition information.

Property Name Type Definition
Calcium SEScalarMass
ElapsedTime SEScalarTime
FatDigestionRate SEScalarMassPerTime
Sodium SEScalarMass
Protein SEScalarMass
CarbohydrateDigestionRate SEScalarMassPerTime
Water SEScalarVolume
Fat SEScalarMass
ProteinDigestionRate SEScalarMassPerTime
Carbohydrate SEScalarMass

The following tables describe the assessments that may be performed on the patient


ComprehensiveMetabolicPanel
Property Name Type Definition
Calcium SEScalarMassPerVolume About half of the calcium in the blood is attached to proteins, mainly albumin. For this reason, the calcium blood test can be misleading, and sometimes needs tests to confirm the result.
Potassium SEScalarAmountPerVolume Measures the amount of potassium in the fluid portion (serum) of the blood. Potassium (K+) helps nerves and muscles communicate. It also helps move nutrients into cells and waste products out of cells.
Glucose SEScalarMassPerVolume Measures the amount of a sugar called glucose in a sample of your blood.
BUN SEScalarMassPerVolume BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down.
Sodium SEScalarAmountPerVolume Measures the amount of sodium in the blood.
AST SEScalarMassPerVolume AST (aspartate aminotransferase) is an enzyme found in high amounts in liver, heart, and muscle cells. It is also found in lesser amounts in other tissues.
Chloride SEScalarAmountPerVolume Chloride is a type of electrolyte. It works with other electrolytes such as potassium, sodium, and carbon dioxide (CO2). These substances help keep the proper balance of body fluids and maintain the body's acid-base balance.
Creatinine SEScalarMassPerVolume Measures the level of creatinine in the blood. This test is done to see how well your kidneys work.
Albumin SEScalarMassPerVolume Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.
TotalProtein SEScalarMassPerVolume Measures the total amount of two classes of proteins found in the fluid portion of your blood. These are albumin and globulin.
CO2 SEScalarAmountPerVolume Most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.
ALT SEScalarMassPerVolume Alanine transaminase (ALT) is an enzyme found in the highest amounts in the liver. Injury to the liver results in release of the substance into the blood.
TotalBilirubin SEScalarMassPerVolume Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.
ALP SEScalarMassPerVolume Alkaline phosphatase (ALP) is a protein found in all body tissues. Tissues with higher amounts of ALP include the liver, bile ducts, and bone.

CompleteBloodCount
Property Name Type Definition
WhiteBloodCellCount SEScalarAmountPerVolume Number of white blood cells per volume of blood.
MeanCorpuscularHemoglobin SEScalarMassPerAmount (MCH) Hemoglobin amount per red blood cell.
Hematocrit SEScalar0To1 Volume percentage of red blood cells in the blood.
RedBloodCellCount SEScalarAmountPerVolume Number of red blood cells per volume of blood.
PlateletCount SEScalarAmountPerVolume Number of platelets per volume of blood.
MeanCorpuscularHemoglobinConcentration SEScalarMassPerVolume (MCHC) The amount of hemoglobin relative to the size of the cell (hemoglobin concentration) per red blood cell.
MeanCorpuscularVolume SEScalarVolume (MCV) Average red blood cell size.
Hemoglobin SEScalarMassPerVolume The concentration of hemoglobin in the blood.

PulmonaryFunctionTest

A group of tests that measure how well the lungs take in and release air, and how well they move gases from the atmosphere into the body's circulation.

Property Name Type Definition
ForcedExpiratoryFlow SEScalarVolumePerTime Measures air flow halfway through an exhale.
ForcedExpiratoryVolume SEScalarVolume The amount of air which can be exhaled with force in one breath.
LungVolumePlot SEFunctionVolumeVsTime The lung volume as a function of time from the pulmonary function test.
ForcedVitalCapacity SEScalarVolume The amount of air which can be forcibly exhaled from the lungs after taking the deepest possible breath.
ResidualVolume SEScalarVolume The amount of air in the lungs after the patient has exhaled completely.
FunctionalResidualCapacity SEScalarVolume The volume of air in the lungs at the end of a normal exhaled breath.
InspiratoryReserveVolume SEScalarVolume The difference between the maximum lung volume and the volume at the end of a normal inhalation.
SlowVitalCapacity SEScalarVolume The amount of air that can be exhaled slowly after the deepest possible inhalation.
ExpiratoryReserveVolume SEScalarVolume Difference between the amount of air in the lungs after a normal exhale and the amount after an exhale with force.
VitalCapacity SEScalarVolume The volume of air that can be exhaled from the lungs after the deepest possible inhalation.
InspiratoryCapacity SEScalarVolume The difference between the maximum lung capacity and the volume at the end of a normal tidal volume exhalation.
MaximumVoluntaryVentilation SEScalarVolume The amount of air that can be breathed in and out during 1 minute.
PeakExpiratoryFlow SEScalarVolumePerTime Air flow during forced exhale of the deepest possible breath.
TotalLungCapacity SEScalarVolume The volume of air in the lungs after the deepest possible inhalation.

Urinalysis

Amount of yeasts viewed.

Property Name Type Definition
Glucose Enum Glucose is normally not present in urine. When glucose is present, the condition is called glucosuria.
Blood Enum This test is used to detect hemoglobin in the urine (hemoglobinuria). Hemoglobin is an oxygen-transporting protein found inside red blood cells (RBCs). Its presence in the urine indicates blood in the urine (known as hematuria).
Ketone Enum Ketones are not normally found in the urine. They are intermediate products of fat metabolism. They can form when a person does process enough carbohydrates.
Nitrite Enum This test detects nitrite and is based upon the fact that many bacteria can convert nitrate to nitrite in the urine.
SpecificGravity SEScalar A measure of urine concentration that can be determined using a chemical test.
Urobilinogen SEScalarMassPerVolume Urobilinogen is normally present in urine in low concentrations. It is formed in the intestine from bilirubin, and a portion of it is absorbed back into the bloodstream.
Appearance Enum Clarity of the urine.
LeukocyteEsterase Enum Leukocyte esterase is an enzyme present in most white blood cells (WBCs). Normally, a few white blood cells (see microscopic examination) are present in urine and this test is negative. When the number of WBCs in urine increases significantly, this screening test will become positive.
Protein Enum The protein test pad measures the amount of albumin in the urine. Normally, there will not be detectable quantities.
Color Enum Color of the urine.
PH SEScalar
Bilirubin SEScalar Bilirubin is not present in the urine of normal, healthy individuals. Bilirubin is a waste product that is produced by the liver from the hemoglobin of RBCs that are removed from circulation.

ePatientAssessment_Type

Available Patient Assessment types.

Property Name Type Definition
CompleteBloodCount Enum CompleteBloodCountTable
ComprehensiveMetabolicPanel Enum ComprehensiveMetabolicPanelTable
PulmonaryFunctionTest Enum PulmonaryFunctionTestTable
Urinalysis Enum UrinalysisTable

eUrinalysis_PresenceIndicator

Enumeration for presence of a substance.

Property Name Type Definition
NullPresence Enum Not provided in the assessment.
Positive Enum
Negative Enum

eUrinalysis_ClarityIndicator

Enumeration for clarity of a substance.

Property Name Type Definition
NullClarity Enum Not provided in the assessment.
Translucent Enum
SlightlyCloudy Enum
Cloudy Enum
Turbid Enum

eUrinalysis_UrineColor

Enumeration for color of urine.

Property Name Type Definition
NullColor Enum Not provided in the assessment.
PaleYellow Enum
Yellow Enum
DarkYellow Enum

eUrinalysis_MicroscopicObservationType

Enumeration for the observation type.

Property Name Type Definition
NullObservationType Enum Not provided in the assessment.
LowPowerField Enum
HighPowerField Enum

eUrinalysis_MicroscopicObservationAmount

Enumeration for the observation amount.

Property Name Type Definition
NullObservationAmount Enum Not provided in the assessment.
Few Enum
Moderate Enum
Many Enum

The following tables describe the external environment that surrounds the patient


AppliedTemperature

Equipment or clothing activly changing the skin temperature of the patient.

Property Name Type Definition
SurfaceAreaFraction SEScalar0To1 SurfaceArea Fraction of the body that the temperature is being appllied to.
Temperature SEScalarTemperature Temperature of an object held on the patient.
SurfaceArea SEScalarArea SurfaceArea of the patient that the temperature is being appllied to.



Environment

The overall environment of the patient.

Property Name Type Definition
ActiveCooling SEActiveConditioning ActiveConditioningTable
EvaporativeHeatLoss SEScalarPower Total patient heat loss due to evaporation.
ConvectiveHeatTranferCoefficient SEScalarHeatConductancePerArea The proportionality coefficient between the heat flux and the thermodynamic driving force for the flow of heat due to convection.
EvaporativeHeatTranferCoefficient SEScalarHeatConductancePerArea The proportionality coefficient between the heat flux and the thermodynamic driving force for the flow of heat due to evaporation.
AppliedTemperature SEAppliedTemperature AppliedTemperatureTable
ActiveHeating SEActiveConditioning ActiveConditioningTable
RespirationHeatLoss SEScalarPower Total heat loss from the Respiratory System.
RadiativeHeatLoss SEScalarPower Total patient heat loss due to radiation.
ConvectiveHeatLoss SEScalarPower Total patient heat loss due to convection.
RadiativeHeatTranferCoefficient SEScalarHeatConductancePerArea The proportionality coefficient between the heat flux and the thermodynamic driving force for the flow of heat due to radiation.
Conditions SEEnvironmentalConditions EnvironmentalConditionsTable
SkinHeatLoss SEScalarPower Total heat loss from the Respiratory skin.


EnvironmentalConditions

The environmental conditions surrounding the patient.

Property Name Type Definition
ClothingResistance SEScalarHeatResistanceArea Average thermal resistance of all patient clothing.
AirVelocity SEScalarLengthPerTime Velocity of the surrounding air relative to the patient.
AmbientGas List of SESubstanceFractionSubstanceFractionTable
AmbientTemperature SEScalarTemperature Local ambient temperature of the surrounding air/fluid (if submerged).
RelativeHumidity SEScalar0To1 Local ambient ratio of the partial pressure of water vapor to the equilibrium vapor pressure of water at the same temperature.
AmbientAerosol List of SESubstanceConcentrationSubstanceConcentrationTable
Emissivity SEScalar0To1 Efficiency of the patient's surface to emit thermal energy.
AtmosphericPressure SEScalarPressure Local ambient pressure of the surrounding atmosphere.
SurroundingType Enum
AirDensity SEScalarMassPerVolume Local ambient density of the surrounding atmosphere.
MeanRadiantTemperature SEScalarTemperature The uniform temperature of an imaginary enclosure in which the radiant heat transfer from the patient's body is equal to the radiant heat transfer in the actual non-uniform enclosure.
RespirationAmbientTemperature SEScalarTemperature Local ambient temperature of the surrounding air that is inhaled.


ActiveConditioning

Equipment or clothing activly changing the surounding environment of the patient.

Property Name Type Definition
Power SEScalarPower Heat sink/source power. Set to zero to turn off conditioning.
SurfaceAreaFraction SEScalar0To1 SurfaceArea Fraction of the body that is being affected.
SurfaceArea SEScalarArea SurfaceArea of the body that is being affected.

ThermalApplication

Create an external heat source.

Property Name Type Definition
ActiveCooling SEActiveConditioning ActiveConditioningTable
AppliedTemperature SEAppliedTemperature AppliedTemperatureTable
ActiveHeating SEActiveConditioning ActiveConditioningTable

ChangeEnvironmentConditions

The environment conditions to change.

Property Name Type Definition
ConditionsFile String File containing an environment conditions objet with properties to set in the environmental conditions.
Conditions SEEnvironmentalConditions EnvironmentalConditionsTable

InitialEnvironmentConditions

The configuration of the environment to use during stabilization.

Property Name Type Definition
ConditionsFile String File containing an environment conditions objet with properties to set in the environmental conditions.
Conditions SEEnvironmentalConditions EnvironmentalConditionsTable

The following tables describe the anesthesia machine


AnesthesiaEvent
Property Name Type Definition
OxygenBottleOneExhausted Enum
OxygenBottleTwoExhausted Enum
ReliefValveActive Enum

AnesthesiaMachineChamber

A vaporization chamber that can be filled with a particular substance for inhalation.

Property Name Type Definition
Substance SESubstance SubstanceTable
SubstanceFraction SEScalar0To1 The fraction of the substance supplied by the vaporizer chamber.


AnesthesiaMachineOxygenBottle

A bottle of Oxygen.

Property Name Type Definition
Volume SEScalarVolume Amount of oxygen in the bottle.


AnesthesiaMachine

Amount of oxygen in the bottle.

Property Name Type Definition
Connection Enum
PositiveEndExpiredPressure SEScalarPressure The pressure above atmospheric pressure that exists in the lungs at the end of expiration.
OxygenSource Enum
ReliefValvePressure SEScalarPressure Pressure at while the valve opens to prevent a build up of pressure in the system.
OxygenBottleTwo SEAnesthesiaMachineOxygenBottle AnesthesiaMachineOxygenBottleTable
InspiratoryExpiratoryRatio SEScalar The ratio of time spent in the inspiratory phase vs the expiratory phase of respiration.
OxygenFraction SEScalar0To1 The fraction of the fresh gas inlet flow that is oxygen.
VentilatorPressure SEScalarPressure The pressure of the ventilator.
LeftChamber SEAnesthesiaMachineChamber AnesthesiaMachineChamberTable
PrimaryGas Enum
OxygenBottleOne SEAnesthesiaMachineOxygenBottle AnesthesiaMachineOxygenBottleTable
RespiratoryRate SEScalarFrequency The prescribed rate of positive-pressure ventilation.
InletFlow SEScalarVolumePerTime The total fresh gas inlet flow.
RightChamber SEAnesthesiaMachineChamber AnesthesiaMachineChamberTable

OxygenTankPressureLoss

The active oxygen tank losses pressure.


VaporizerFailure

The vaporizer fails.

Property Name Type Definition
Severity SEScalar0To1 Severity of the failure from 0 to 1.

TubeCuffLeak

A leak in the tube cuff.

Property Name Type Definition
Severity SEScalar0To1 Severity of the leak from 0 to 1.

SodaLimeFailure

A soda lime failure.

Property Name Type Definition
Severity SEScalar0To1 Severity of the failure from 0 to 1.

AnesthesiaMachineConfiguration

The configuration of the anesthesia machine to use.

Property Name Type Definition
Configuration SEAnesthesiaMachine AnesthesiaMachineTable
ConfigurationFile String File containing an anesthesia machine objet with properties to set in the system anesthesia machine.

MaskLeak

A leak in the mask.

Property Name Type Definition
Severity SEScalar0To1 Severity of the leak from 0 to 1.

ExpiratoryValveObstruction

An obstruction in the expiritory valve.

Property Name Type Definition
Severity SEScalar0To1 Severity of the obstruction from 0 to 1.

VentilatorPressureLoss

The ventilator losses pressure.

Property Name Type Definition
Severity SEScalar0To1 Severity of the loss from 0 to 1.

YPieceDisconnect

The Y Piece becomes disconnected.

Property Name Type Definition
Severity SEScalar0To1 Severity of the leak from 0 to 1.

InspiratoryValveObstruction

An obstruction in the inspiritory valve.

Property Name Type Definition
Severity SEScalar0To1 Severity of the obstruction from 0 to 1.

OxygenWallPortPressureLoss

The wall port losses oxygen pressure.


ExpiratoryValveLeak

A leak in the expiritory valve.

Property Name Type Definition
Severity SEScalar0To1 Severity of the leak from 0 to 1.

InspiratoryValveLeak

A leak in the inspiratory valve.

Property Name Type Definition
Severity SEScalar0To1 Severity of the leak from 0 to 1.

The following tables describe the ECG


ElectroCardioGram

Generic ECG machine to assess the heart rhythm.

Property Name Type Definition
Lead3ElectricPotential SEScalarElectricPotential The amount of electric potential given off by lead 3 of the ECG.

ElectroCardioGramWaveformList

Active indicies of the WaveForm Data used to interpolate the current electric potential.


ElectroCardioGramWaveform

The amount of electric potential given off by lead 12 of the ECG.

Property Name Type Definition
Lead Enum Lead number of the waveform provided.
TimeStep SEScalarTime Time step of the data provided.
Data SEFunctionElectricPotentialVsTime Dataset of a full heart cycle.
Rhythm Enum Rhythm type of the waveform provided.

The following tables describe the inhaler


Inhaler

Generic inhaler for substance administration.

Property Name Type Definition
MeteredDose SEScalarMass Dosage of substance.
SpacerVolume SEScalarVolume Volume of a spacer, if used.
Substance SESubstance SubstanceTable
NozzleLoss SEScalar0To1 Fraction of substance lost from the inhaler. -.



InhalerConfiguration

The configuration of the inhaler to use.

Property Name Type Definition
Configuration SEInhaler InhalerTable
ConfigurationFile String File containing an inhaler objet with properties to set in the system inhaler.

The following tables describe substances used in Pulse


SubstanceFraction

A fractional amount associated with a substance.

Property Name Type Definition
Amount SEScalar0To1 The fractional amount of the substance.
Substance SESubstance SubstanceTable

LiquidSubstanceQuantity

The quantity of a solid,liquid, or gas substance in a liquid compartment.

Property Name Type Definition
MassExcreted SEScalarMass The total mass of a substance excreted in the specified compartment.
MassCleared SEScalarMass The total mass of a substance cleared in the specified compartment.
MassDeposited SEScalarMass The total mass of a substance deposited on the wall of the compartment.
Mass SEScalarMass The total mass of a substance in the specified compartment.
Molarity SEScalarAmountPerVolume The molarity of a substance in the specified compartment.
PartialPressure SEScalarPressure The partial pressure of a substance in the specified compartment.
Saturation SEScalar0To1 The saturation of a substance in the specified compartment. (if applicable, like O2 and CO2)
Concentration SEScalarMassPerVolume The concentration of a substance in the specified compartment.

SubstancePhysicochemicals
Property Name Type Definition
LogP SEScalar The octanol-water partition coefficient.
AcidDissociationConstant SEScalar A quantitative measure of the strength of an acid in solution .
IonicState Enum
BindingProtein Enum
FractionUnboundInPlasma SEScalar0To1 Fraction of the substance in the plasma that is unbound.
OralAbsorptionRateConstant SEScalar Rate at which an orally administered drug leaves the GI tract.
BloodPlasmaRatio SEScalar The ratio of the substance in the blood versus the plasma.

SubstanceCompound

A compound made up of several substances.

Property Name Type Definition
Name String The unique name of the compound.
Components List of SESubstanceCompoundComponentSubstanceCompoundComponentTable

SubstanceClearance
Property Name Type Definition
RenalReabsorptionRate SEScalarMassPerTime
RenalTransportMaximum SEScalarMassPerTime
RenalExcretionRate SEScalarMassPerTime
RenalFiltrationRate SEScalarMassPerTime
FractionMetabolizedInGut SEScalar0To1
FractionUnboundInPlasma SEScalar0To1
ChargeInBlood Enum
FractionExcretedInFeces SEScalar0To1
IntrinsicClearance SEScalarVolumePerTimeMass
RenalClearance SEScalarVolumePerTimeMass
SystemicClearance SEScalarVolumePerTimeMass
RenalReabsorptionRatio SEScalar
FractionExcretedInUrine SEScalar0To1
GlomerularFilterability SEScalar

SubstanceTissuePharmacokinetics
Property Name Type Definition
Name String The tissue compartment/area/organ name impacted.
PartitionCoefficient SEScalar Represents the ability of a substance to diffuse across a membrane. Calculated using the physiochemical properties of a substance.

SubstancePharmacodynamics
Property Name Type Definition
EC50 SEScalarMassPerVolume
NeuromuscularBlock SEScalarNegative1To1
EMaxShapeParameter SEScalar This used to create a sigmoid shape response. i.e. the steepness parameter in the EMax equation.
TidalVolumeModifier SEScalarNegative1To1
PupillaryResponse SEPupillaryResponse PupillaryResponseTable
Sedation SEScalarNegative1To1
TubularPermeabilityModifier SEScalarNegative1To1
RespirationRateModifier SEScalarNegative1To1
DiastolicPressureModifier SEScalarNegative1To1
HeartRateModifier SEScalarNegative1To1 A modifier representing the effect of the drug on the heart rate.
SystolicPressureModifier SEScalarNegative1To1
Bronchodilation SEScalarNegative1To1

SubstanceAerosolization

Data for if a substance was to be aerosolizized.

Property Name Type Definition
BronchioleModifier SEScalarNegative1To1 Factor to characterize the localized bronchiole effects -1 is full constriction, 1 is full dilation.
ParticulateSizeDistribution SEHistogramFractionVsLength Histogram of Particle Fraction Vs. Size.
InflammationCoefficient SEScalar0To1 Factor to characterize the inflamation of respiratory tract tissue caused by this substance.

SubstanceManager

Substance

The concentration of the substance.

Property Name Type Definition
Name String The unique name of the substance.
RelativeDiffusionCoefficient SEScalar Represents the ability of the substance to diffuse across a membrane. A proportionality of the solubility and the square root of the molecular weight as defined relative to oxygen.
SystemicMassCleared SEScalarMass The total amount of mass that has been systemically cleared.
MassInBlood SEScalarMass Amount of mass of this substance that is in the blood.
DiffusingCapacity SEScalarVolumePerTimePressure Calculated value representing the ability of a gas to cross the respiratory membrane.
EndTidalFraction SEScalar0To1 The fraction of gas in the trachea that consists of the substance at the end of each respiratory cycle.
EndTidalPressure SEScalarPressure The pressure of gas in the trachea that consists of the substance at the end of each respiratory cycle.
MolarMass SEScalarMassPerAmount Molar mass of the substance.
PlasmaConcentration SEScalarMassPerVolume Calculated concentration of a substance in the plasma.
Aerosolization SESubstanceAerosolization SubstanceAerosolizationTable
Density SEScalarMassPerVolume Mass density of a substance.
PD SESubstancePharmacodynamics SubstancePharmacodynamicsTable
Clearance SESubstanceClearance SubstanceClearanceTable
MassInBody SEScalarMass Total Amount of mass of this substance that is in the body.
MassInTissue SEScalarMass Amount of mass of this substance that is in the tissue.
State Enum
MaximumDiffusionFlux SEScalarMassPerAreaTime Maximum mass flux of a substance when diffusing across a membrane.
SolubilityCoefficient SEScalarInversePressure Represents the ability of a substance to dissolve in a solution.
TissueConcentration SEScalarMassPerVolume Concentration of this substance that is in the tissue.
PK SESubstancePharmacokinetics SubstancePharmacokineticsTable
MichaelisCoefficient SEScalar The concentration gradient at which the flux is half of the MaxDiffusionFlux.
AlveolarTransfer SEScalarVolumePerTime Calculated rate of transfer that occurs during gas exchange.
BloodConcentration SEScalarMassPerVolume Concentration of this substance that is in the blood.

SubstancePharmacokinetics

Data associated with movement of drugs within the body.

Property Name Type Definition
Physicochemicals SESubstancePhysicochemicals SubstancePhysicochemicalsTable
TissueKinetics Collection CollectionTable

SubstanceConcentration

A concentration amount associated with a substance.

Property Name Type Definition
Substance SESubstance SubstanceTable
Concentration SEScalarMassPerVolume The concentration of the substance.

GasSubstanceQuantity

The quantity of a gas substance in a gas compartment.

Property Name Type Definition
VolumeFraction SEScalar0To1 The amount of a substcane in the specified comparment as a fraction of all substance volume.
PartialPressure SEScalarPressure The partial pressure of a substance in the specified compartment.
Volume SEScalarVolume The total volume of a substance in the specified compartment.

SubstanceQuantity

Basic Substance Quantity.


LiquidSubstanceQuantity

The quantity of a solid,liquid, or gas substance in a liquid compartment.

Property Name Type Definition
MassExcreted SEScalarMass The total mass of a substance excreted in the specified compartment.
MassCleared SEScalarMass The total mass of a substance cleared in the specified compartment.
MassDeposited SEScalarMass The total mass of a substance deposited on the wall of the compartment.
Mass SEScalarMass The total mass of a substance in the specified compartment.
Molarity SEScalarAmountPerVolume The molarity of a substance in the specified compartment.
PartialPressure SEScalarPressure The partial pressure of a substance in the specified compartment.
Saturation SEScalar0To1 The saturation of a substance in the specified compartment. (if applicable, like O2 and CO2)
Concentration SEScalarMassPerVolume The concentration of a substance in the specified compartment.

GasSubstanceQuantity

The quantity of a gas substance in a gas compartment.

Property Name Type Definition
VolumeFraction SEScalar0To1 The amount of a substcane in the specified comparment as a fraction of all substance volume.
PartialPressure SEScalarPressure The partial pressure of a substance in the specified compartment.
Volume SEScalarVolume The total volume of a substance in the specified compartment.

SubstanceQuantity

Basic Substance Quantity.


The following tables describe anatomical compartments


FluidCompartment
Property Name Type Definition
OutFlow SEScalarVolumePerTime
InFlow SEScalarVolumePerTime
Name String
Pressure SEScalarPressure
Volume SEScalarVolume

LiquidCompartment
Property Name Type Definition
OutFlow SEScalarVolumePerTime
InFlow SEScalarVolumePerTime
Name String
SubstanceQuantities List of SELiquidSubstanceQuantityLiquidSubstanceQuantityTable
Volume SEScalarVolume
PH SEScalar
Pressure SEScalarPressure

GasCompartment
Property Name Type Definition
OutFlow SEScalarVolumePerTime
InFlow SEScalarVolumePerTime
Name String
SubstanceQuantities List of SEGasSubstanceQuantityGasSubstanceQuantityTable
Volume SEScalarVolume
Pressure SEScalarPressure

TissueCompartment
Property Name Type Definition
TissueToPlasmaAlphaAcidGlycoproteinRatio SEScalar
Name String
AcidicPhospohlipidConcentration SEScalarMassPerMass
MatrixVolume SEScalarVolume
TissueToPlasmaLipoproteinRatio SEScalar
TotalMass SEScalarMass
TissueToPlasmaAlbuminRatio SEScalar
NeutralLipidsVolumeFraction SEScalar0To1
NeutralPhospholipidsVolumeFraction SEScalar0To1

ThermalCompartment
Property Name Type Definition
HeatTransferRateIn SEScalarPower
Name String
Temperature SEScalarTemperature
HeatTransferRateOut SEScalarPower
Heat SEScalarEnergy

The following tables describe a simulation scenario


Scenario
Property Name Type Definition
Name String
EngineState String
Description String
PatientConfiguration SEPatientConfiguration PatientConfigurationTable

The following tables describe general enumerations


eSide

Enumeration for left/right side.

Property Name Type Definition
NullSide Enum Not provided.
Left Enum Left side.
Right Enum Right side.

eGate

Enumeration for an open/closed gate.

Property Name Type Definition
NullGate Enum Not provided.
Open Enum Gate is open.
Closed Enum Gate is closed.

eSwitch

Enumeration for a on/off switch.

Property Name Type Definition
NullSwitch Enum Not provided.
Off Enum Switch is off.
On Enum Switch is on.

eCharge

Enumeration for electrical charge.

Property Name Type Definition
NullCharge Enum Not provided.
Negative Enum Charge is negative.
Neutral Enum Charge is neutral.
Positive Enum Charge is positive.